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The discovery of new potential targets arising from micro array studies gives the opportunity to activate or inhibit different new ER-modulating effectors for innovative therapeutic interventions.
However, there are some fundamental mathematical differences between SAGE and micro array studies [ 17, 29].
The amount dissected was determined both by the length of cancer available in the core, and also to enable preservation of any remaining cancer tissue for tissue micro array studies.
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An earlier micro array study performed by Tchkonia et al [ 41] investigated differences in gene expression levels between differentiated and undifferentiated adipocytes derived from subcutaneous, visceral, and mesenteric adipose tissue.
We analyzed a total of 10 genes within the network by QPCR: 6 derived from the micro array study (C3, fn1, foxo5, notch1a, notch1b, and plg; Figure 2); 2 derived from the microarray study and corroborated by CTD (ass1, pik3r1), and 2 bridging genes corroborated by CTD (akt2, nfkb2).
Micro-array studies were previously described by De Vos et al. [1] and Pozo et al. [47].
In recent years, micro-array studies have been increasingly used to analyse tissue or cell response to a given stimuli [3], [22] [25], and provide a lot of data for analysis.
To confirm our observation from our micro-array studies, we quantitated the mRNA levels of HDAC3 in MS patients (n = 12) and controls (n = 12) using real time RT-PCR.
ARCP and SRS carried out the Tissue Micro-array studies and the immunohistochemistry analysis.
FA, AA, GH: micro-array studies at 1,5 and 15 d.p.i.
For many cancer types, however, several micro-array studies have been performed to develop prognostic models.
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