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The swimming time of the scopolamine-treated mice within the platform quadrant was significantly reduced by treating with MEXX (100 mg/kg) in probe session.
The cognitive performance of individual mice within the transgenic group were inversely related to the amount of Aβ deposited in the frontal cortex and hippocampus.
But because even that won't eliminate outcome differences, every result should be replicated with a new batch of mice within the same lab, and perhaps even elsewhere, before it's published.
There is nothing restricting aggressive mice from outcompeting docile mice within the groups.
There were no significant differences between treated and untreated mice within the same strain.
Splenocytes were isolated from naive and immunized mice and pregnant and non pregnant mice within the respective groups.
Unpaired t-test was used to detected difference between PRKO and WT mice within the same sex.
Although the latter will be non-functional in SLE-afflicted mice, within the healthy injected mice we can still expect suppression of CD4 effector cells by CD4 Tregs.
As reported for normally sighted animals in previous studies, we found a clear aversion to light by WT mice within the first 5 minutes of our test.
There were no significant differences in normalized forelimb or hindlimb grip strength between treated and untreated mice within the same strain during the trial (Table S1).
These results indicate that no active tolerance was achieved in the mice within the Islet-Tx and Edmonton-Tx groups since the injection of donor-derived antigens broke the state of immune incompetence leading to graft rejection [20].
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