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The present work has been designed in order to test the effects of mobile phone radiation on spatial learning and memory in mice Mus musculus Balb/c using the Morris water maze (a hippocampal-dependent spatial memory task), since there is just one other study on mice with very low SAR level (0.05 W/kg) showing no effects.
Despite previous reports of phosphorothioate-modified oligonucleotide toxicity, clones of edited cells are readily isolated and targeted sequence insertions are achieved in rats and mice with very high frequency, allowing for homozygous loxP site insertion at the mouse ROSA locus in particular.
One G3 pedigree (Figure 1A) contained mice with very low grip strength (Figure 1B).
Ctgf Lo/Lo mice were crossed to Ctgf heterozygous knockouts (Ctgf KO/+) to generate mice with very low Ctgf expression (Ctgf Lo/KO).
We have shown that B cells presenting the MOG peptide by MHCII can participate in the process of negative selection, leading to mice with very few T cells expressing the transgenic TCR.
Other laboratories are also making efforts to generate similar human FXN BAC transgenic mice with very large pure GAA repeats.
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The hepatic effects of ciprofibrate, a potent peroxisome proliferator, were evaluated in male C57BL/6N mice, a mouse strain with very low incidence of spontaneous liver tumour development.
Thus, like eosinophilic inflammation, AHR was also sustained after multiple OVA challenges in mice sensitized with very low doses of LPS but not in mice sensitized by the higher, but still moderate, dose of 10 1 μg LPS.
However, in transgenic mice with a very low penetrance, tumors arise stochastically with a very long latency period.
To directly test whether robust neutrophilic inflammation is required to develop severe acute and chronic infection, we treated mice with a very low dose (10 μg) of the 1A8 Ly6G-specific antibody 24 h prior to infection to partially reduce neutrophil levels (Brandes et al., 2013).
The goal of data set G was to identify genes with altered expression in the liver tissues of two mouse models with very low HDL cholesterol levels (treatment groups) as compared to inbred control mice.
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