Finally, a USB gaming mouse with support for 1000-Hz scanning frequency is used, which lowers the error associated with the input hardware from 8 ms (125 Hz default scan frequency) to 1 ms.
Next month, Yoder will begin a year-long research sabbatical in Europe and northwestern Madagascar exploring species dynamics in mouse lemurs with support from a Guggenheim Fellowship and a Humboldt Fellowship.
We identify 2788 likely uaRNAs in human and 2294 in mouse with strong support from the CAGE data.
The higher hippocampal uptake in mice with dex treatment supports the findings of D'hulst et al. [19], who found a mild (4. 6.0 %) increase in the binding of [18F]- or [11C]flumazenil binding in dex-treated humans.
Our studies indicate that a T cell response against T. gondii can develop in mice with defective autophagy supporting the existence of another mechanism by which autophagy promotes resistance against T. gondii.
A review of the literature pertaining to mice and H. pylori transmission revealed the pervasive use of mice in animal models and repeated demonstration of the ability to inoculate mice with H. pylori, supporting the plausibility of mice playing a role in transmission.
Thus, the timing and pattern of plaque distribution after microinjection of tg44 mice with RML scrapie supported our previous hypothesis that spread of infectivity occurred via dissemination with brain interstitial fluid (ISF) in perivascular regions of gray and white matter and in interaxonal spaces of white matter tracts [ 31].
Overall, our biochemical, histological and gene transfer experiments using novel model mice with disease-causing mutations support the efficacy of glycotherapy in dystroglycanopathies.
Ex vivo radiometric analysis of the livers revealed an increase in the signal in old L2AKO mice compared with Ctr mice, in support of higher oxidative stress in the CMA-incompetent mice (Fig. 7E).
Tetanic conditioning revealed a marked difference in the ability of hippocampus slices from Irs2−/− mice to support LTP, with potentiation of fEPSP being significantly reduced in slices from transgenic animals as compared with WT (n = 6 mice of each genotype, at least 3 slices per mouse, P < 0.001, Fig. 2 A ).
