Sentence examples for mice with single from inspiring English sources

However, as depression is a complex disorder in which minor changes of many genes as well as environmental factors (including epigenetic programming) play a causal role and determine the phenotype, the use of mice with single gene mutations needs to be critically discussed when attempting to create a genetic animal model of depression.

In the first pilot studies, mice with single and double inoculations of FaDu and A431 cells were studied.

We investigated the mechanism and function of nuclear anchorage in skeletal muscle cells by generating mice with single and double-disruption of the KASH-domain-containing genes Syne1 (also known as Syne-1) and Syne2 (also known as Syne-2).

After 12 13 days, PET imaging was performed with [methyl-11C]-ZEGFR:2377-ST-CH3 and, for mice with single xenografts, ≥3.5 h later with [methyl-11C]-ZTaq:3638-ST-CH3.

In this study, the impact of individual MHC class I alleles on the Ly49 receptor repertoire was tested and modelled in mice with single MHC class I alleles.

We observed that there was an average of 15-fold reduction (P = 0.0079) in the organ load of mice with single dose vaccination (Figure 4A).

Previous efforts to create mice with single-copy BRCA1 mutations had uncertain results because the mice failed to show the pattern of human cancers.

Upon crossing these mice with single-transgenic ZFHD1::miceT1 mice, PEF from one out of six embryos showed inducible STAT1 expression.

Moreover, the combination treatments prolonged median survival among mice, as opposed to mice treated with single treatments or control.

(a) Basal ET concentration in mice administered with single dose of saline (1-day control), n = 7.

Basal tissue distribution of ET related metabolites in mice fed with single dose of saline (1-day control), n = 7.