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Using CRISPR to insert this same system into zygotes, Jaenisch's team reported making conditional mice with relatively "high efficiency"—about 16% of the zygotes led to mouse pups with the correct mutations.
Brain MRgluc, estimated only in the non-insulin-treated mice with relatively stable plasma glucose levels averaged in a non-fasted state about 3.2 mg/min/100 g, a value very comparable to that reported by our group in mice with arterial catheters (2.2 mg/min/100 g) [9].
The western blot data suggest that the topical application of peptides (PIP-18[59 67] and PIP-18[59 6759–67]) modulands NF-kB mediated wound repair in mice with relatively little haemolytic (100–1.56 μg/ml) and cytotoxic (1000–3.125 μg/ml) effects evident on human cells in vitro.
Our results escalate this surprise further as genetic deletions of the neuronal enzyme TPH2 and the combination of TPH1 plus TPH2 enzymes also produced viable mice with relatively subtle alterations in behavior.
We reported previously that mice with relatively high expression of HCV core display markers of oxidant stress [ 9, 10, 17].
Decreasing the tumour burden by radiotherapy before PDT vaccine treatment allows curing mice with relatively large malignant growth.
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They infected mice with a relatively harmless variety of the Semliki Forest virus (SFV), a relative of chikungunya.
Our expression analysis of Atp10a was performed in mice with a relatively homogenous C57BL/6J genetic background that overlaps with, but is not the same as that used in the other studies.
Positive founders were genotyped and back-crossed with C57BL6 for more than ten generations to produce mice with a relatively pure C57BL6 background.
Our laboratory found a more modest protective role for TLR4 during lower respiratory tract infection by S. pneumoniae, as reflected by a reduced survival and a slightly enhanced bacterial outgrowth after intranasal infection of C3H/HeJ mice with a relatively low infectious dose (Branger et al., 2004).
It has been reported that a deficiency of Fog2 (Friend of Gata 2), causes loss of the accessory lobe and anterior right medial lobe of the mouse lung with relatively good preservation of other structures [142] and that a Fog2-Gata4 isteracritical critical for the development of normal pulmonary lobar structure [143].
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