Sentence examples for mice with existing from inspiring English sources

She and her colleagues predicted that both the cellular stress response and the mitochondrial damage could be reversed by treating obese mice with existing compounds.

To determine the potential translational relevance of the Ag-PLG tolerance procedure for treating established autoimmune disease, we next sought to determine if therapeutic administration of Ag-PLG would be effective in treating mice with existing symptoms of EAE.

When treatment was applied to mice with existing tumours, a reduction in tumour volume was observed by the end of the first week of treatment, and tumour growth continued to be depressed throughout the course of the study.

Comparison of our promising findings in mice with existing literature revealed that the Hydralazine dose which we used in our animal studies, and which had been established as an optimum de-methylating dose in previous cancer studies (5 mg/kg/day), does not lower blood pressure and was below the anti-hypertensive dose commonly used in mice (50 mg/kg applied up to four times daily).

Overall, our results in two transgenic mouse models with existing AD-related pathology suggest that low-energy NIr treatment can reduce characteristic pathology, oxidative stress and mitochondrial dysfunction in susceptible regions of the brain.

In designing the experiment, we chose to construct htt N118 cDNA genes with 82 glutamines to express via the mouse PrP.Xho vector so that the new mice could be compared with existing N171-82Q mice (8).

To facilitate comparisons of any mice generated with these constructs with existing lines of mice expressing humanized APP constructs, we used two strategies to produce transgenic mice.

Taken together, our data demonstrate that HBO's neuroprotective effect is related to the reduction of the T cells sequestered in mice brains; and corroborate with existing literature, in which T lymphocytes, mainly αβ CD8+ T cells, are implicated in CM pathology [14], [37] No immunolabeling was detected on T lymphocytes in the absence of mAbs (data not shown).

Phenotypic similarity with existing mouse models of lissencephaly led us to screen a cohort of patients with developmental brain anomalies.

This is a different approach than focusing on de novo CNV in human subjects [24], [25]; examination of de novo duplications shares more in common with existing mouse mutagenesis strategies.

This synthesis is intended to provide a useful source of reference when studying the molecular controls of hair follicle growth and differentiation, and whenever the hair phenotypes of a newly generated mouse mutant need to be compared with existing ones.