Sentence examples for mice with dysfunctional from inspiring English sources

Thus, our findings link the anxiety-related behavioral deficits observed in Clock-Δ19 mice with dysfunctional gamma oscillatory tuning across limbic circuits and suggest that alterations in limbic oscillatory circuit function induced by circadian gene polymorphisms may contribute to the behavioral manifestations seen in bipolar mania.

Interestingly, overexpression of human SOST in transgenic mice resulted in an additional phenotype with fused or missing digits of the fore and hind limbs, reminiscent of the phenotype of mice with dysfunctional Lrp4 [32].

Moreover deletion of p21 in telomerase-deficient mice with dysfunctional telomeres prolongs the lifespan [ 34].

The phenotype was aggravated in brains of late-generation TERC−/− mice with dysfunctional telomeres.

Fourth, Sod-2 haploinsufficiency did not accelerate murine aging, even in mice with dysfunctional telomeres [ 19].

Similar aberrations have been observed in tumours from transgenic mice with dysfunctional telomeres (Artandi et al, 2000).

In food-deprived mice the lipidation of LC3 was impaired and abundance of p62 increased in aorta of aged compared to young mice, consistent with dysfunctional autophagy induction.

They engineered two mice strains with dysfunctional receptors.

Intrigued, Turek joined with endocrinologist Joseph Bass, also at Northwestern, to study the effects of regular and high-fat diets in normal mice and mice with a dysfunctional Clock gene.

Moreover, in Largemyd mice, with hypoglycosylated and dysfunctional α-DG, the hindbrain has disorganized and missing nuclei [16].

Staggerer mice present decreased fasting glucose levels, improved glucose tolerance and increased insulin sensitivity We have previously demonstrated that homozygous staggerer (sg/sg) mice (with decreased and dysfunctional RORα levels) display a lean phenotype.