Sentence examples for mice with doubly from inspiring English sources

Exposure of transgenic mice to maneb and paraquat showed a higher level dopaminergic neurotoxicity in mice with doubly mutated α-synuclein compared with mice expressing normal wild-type human α-synuclein (Thiruchelvam et al. 2004).

We crossed Notch2flox/Notch2flox mice with mice doubly heterozygous for the Alb1-Cre transgene and either the Notch2del2 or Notch2del3 alleles.

Interestingly, Chk2 deficiency significantly rescued the survival of Trf1 Δ/Δ K5Cre mice, with one doubly deficient mice surviving for as long as 1 year of age compared to a maximum survival of 4 days for single Trf1-deficient littermates (Fig. 1A).

Primary neurons were prepared from tau knockout mice and doubly transfected with APP and GFP.

Following 7 days CldU and 7 days IdU labeling, 4.3±0.5% of β cells (5500 insulin+ cells counted in duct-ligated pancreas of five mice) were doubly labeled compared with the ≤1.5% reported for neonatal, pregnant or pancreatectomized mice.

To obtain mice deficient in both B and T cells, heterozygous female mice deficient in B cells and T cells were crossed with doubly deficient males, and offspring were investigated for the absence of B cells and T cells by cytofluorimetric analysis.

Consistent with the phenotype of STAT5a and STAT5b singly deficient mice, the doubly deficient animals exhibit defective development of mammary glands and impaired T cell proliferation in response to IL-2.

Using the sensitive DNA profiling technique, LSSP-PCR (Low-Stringency single Specific Primer PCR), we previously showedthat hearts of BALB/c mice doubly infected with JG and Col1.7G2 T. cruzi populations were mainly colonized by JG strain, while Col1.7G2 was preponderant in the rectum and all other analyzed tissues [2].

The solutions were freshly prepared with doubly distilled water.

Physical activity was measured over two-week periods with doubly labeled water and doubly labeled water validated triaxial accelerometers, and body fat gain was measured with isotope dilution.

All initial measurements and follow-up measurements in 22 subjects were performed with doubly labeled water.