Sentence examples for mice with defects from inspiring English sources

Indeed, mice with defects in JNK1 expression in adipose tissue are protected against hepatic steatosis.

However, mutant mice with defects in TGF-beta36, FGF37,38,39, Noggin40, and Notch41 signaling all have digits, while CHL2 expression has been found to be restricted to chondrocytes of various developing joint cartilage surfaces and connective tissues in reproductive organs42.

Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.

Although C. albicans induced LC3-II formation in macrophages, myeloid cell-specific ATG7 mice with defects in autophagy did not display an increased susceptibility to disseminated candidiasis.

Now, one team has found that mice with defects in DNA repair are especially prone to tumors.

He and his colleagues created mice with defects in one of two DNA polymerases critical for proofreading.

Consistent with this idea, the tumors observed in p53 defective mice with telomerase defects are characterized by numerous chromosomal rearrangements that recapitulate the classes of aberrant chromosomes observed in many solid tumors [8], [10].

For example, Bag6 knockout mice die with defects of kidney, lung and brain formation as a result of dysregulation of apoptosis and cell proliferation (Fabian et al., 2005).

In mouse models, mice with specific defects in folate transport had higher rates of neural tube defects after in utero arsenic exposure than wild-type mice similarly exposed [ 5, 11].

Mice lacking SIRT1 survive when outbred but yield smaller, sterile mice with developmental defects [ 10, 11].

When the tissue was transplanted into mice with pituitary defects, levels of missing hormones in their bodies rose to normal.