Sentence examples for mice with animals from inspiring English sources

To test this possibility we crossed Gnat1−/− mice with animals carrying the Gnat2cpfl3 allele, a missense mutation that results in a progressive loss of cone function[20].

To investigate the biologic effects of mTORC1 in the liver, we ablated a key negative regulator of mTORC1, Tsc1, in hepatocytes by crossing Albumin-Cre mice with animals carrying floxed alleles of Tsc1.

Previous studies compared ascorbate supplemented Gulo−/− mice with animals where ascorbate was completely withdrawn for 4 weeks 30– 30.

In order to generate GluLKB1KO mice deleted for both alleles of Lkb1 in proglucagon-expressing enteroendocrine cells, in pancreatic α-cells and in GLP-1+ neurons within the brainstem and elsewhere, we crossed Lkb1 floxed mice with animals carrying a Cre-recombinase transgene under the control of the proglucagon promoter located within a bacterial artificial chromosome (BAC) (Parker et al., 2012).

However, contradictory results have recently been published by Miwa et al. [ 40], who, after crossing decay-accelerating factor (DAF, CD55) and CD59 double knockout mice with animals deficient with various complement components/receptors, demonstrated a crucial role for the alternative but not the classical or lectin pathways.

Crossbreeding the Gαq transgenic mice with animals that had a cardiomyocyte-specific overexpression of catalase reduced both Cys674 sulfonylation and Tyr294/295 nitration, restored SERCA activity, and improved myocyte Ca transients and contraction suggesting that H2O2 was involved in these effects.

Withdrawal significantly increased the Salmonella burden in various tissues of infected mice compared with animals who had placebo withdrawn and decreased the mean survival time.

To examine the effect of dominant negative PEA3 on Wnt1-driven tumorigenesis, we compared tumor latency in MMTV/Wnt1 and bigenic MMTV/Wnt1, MMTV/ΔNPEA3En virgin females, generated by interbreeding MMTV/Wnt1 mice with MMTV/ΔNPEA3En animals.

For all experiments, 6- to 8-week-old female mice with 10 animals per group (total of 30) were used.

Also, the published studies compared germfree mice with conventional animals possessing a complete microbiota, while we only modeled the presence of B. thetaiotaomicron.

Inactivation of ILK in colonic epithelial cells was achieved by crossing the Fabp –Cre mice with ILKflox/flox animals.