Sentence examples for mice with active from inspiring English sources

We have recently showed that CD98 expression is highly upregulated in colonic tissues from mice with active colitis, and that activation of epithelial CD98 aggravates intestinal inflammation [42].

However, although these cells were able to inhibit disease, the population transferred reflected only a subset of natural Tregs in mice with active lupus.

In B/W mice with active lupus, the frequency of natural Tregs, as measured by Foxp3+ expression, was 96±2% in the cells identified by CD4+CD25+CD62LHI expression (Figure 1A).

In order to clarify whether they are sufficient to trigger disease development, we performed adoptive transfer of splenocytes from PPARβ/δ transgenic mice with active disease to wild-type mice, which had previously been depleted of endogenous CD4+ cells.

In this study, the CD4+CD25+CD62LLO Tregs from B/W mice with active disease were isolated by FACS sorting and the suppressor capacity was compared to the CD4+CD25+CD62LHI Treg fraction.

We previously demonstrated that B/W mice with active lupus have a significantly expanded Treg population that is equal to or exceeds the population found in non-autoimmune prone animals[24].

Finally, atherosclerotic plaques in mice infused with active hyaluronidase did display higher glycosaminoglycan content.

In addition to increases in pro-inflammatory cytokines, there were 6 to 84 fold increases in growth factors and chemokines in the BALF of mice treated with active rCARDS toxin including G-CSF, KC, MCP-1, MIP-1α, and MIP-1β (Figure 2 and Table 1).

14– 16 Briefly, hippocampal slices (400  μm) were prepared from 6- to 7-week-old mice injected with active or scrambled control peptides as described for behavioral and biochemical assessment, and allowed to recover in a holding chamber for at least 2 h.

Results of those studies do not necessarily refute our findings because some AhR ligands can activate other signaling pathways (Terzuoli et al. 2010) Transgenic mice with constitutively active AhR have decreased PPAR-α levels (Lee et al. 2010).

The results confirmed that CP-A172 provides mice with both active and passive resistance against a lethal dose of A170 (Table 6).