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The mice will serve as subjects for research into diseases like cancer and diabetes, Ms. Mitchell said, explaining that when complete, its 50,000-square-foot research lab will house 40,000 cages, each with three animals.
We believe that Vav2/Vav3-deficient mice will serve not only as a useful murine model of spontaneous glaucoma, but may also provide a valuable tool in understanding of the pathogenesis of glaucoma in humans, particularly the determinants of altered aqueous outflow and elevated IOP.
These mutant mice will serve as useful models for the study of vertebral malformations.
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Mickey Mouse will serve as a mischievous tour guide on a musical journey through a magical map in a new stage show coming May 25 to Disneyland's Fantasyland Theatre.
For future investigation, in vivo micro-CT imaging would enable us to follow the progression of fracture repair longitudinally over time, with the advantage that each mouse will serve as its own control to allow matched analyses.
Finally, the PI3Kγ KO mouse line will serve as an excellent ADHD model to develop and test novel therapeutic strategies, and represents a true progress in a field where animal models are particularly scarce.
The katun mouse strain will serve as a useful model for further investigations into the molecular pathways underlying ZIC3-associated heterotaxy, and for studies of Zic protein interactions and transcriptional surveillance mechanisms.
This novel mouse model will serve as an important tool to define the cellular and molecular mechanisms by which Cdc42 overexpression affects mammary tumor formation, progression, and metastasis in vivo.
Vhl-deficient mice will thus serve as an unprecedented model to study the early signs of hypoxia intolerance, which in a translational medicine setting could help prevent hypoxia-associated morbidities in susceptible individuals.
The mouse PWD/Ph BAC library will serve as a tool for functional genomics of complex genetic traits with the ultimate goal to identify and clone responsible genes.
Here, we undertook steps to generate a new fully functional, highly expressed mouse CL Pgp that will serve as an improved tool for biophysical studies of the Pgp transport mechanism.
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