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It is possible that vaccines that perform better than LVS in mice will also do so in humans.
These mice will also be a useful resource for future studies to provide insights into the role of MUC16 in organ homeostasis and ovarian cancer both in vitro and in vivo.
Whether PNKP deficiency in mice will also result in microcephaly is yet to be tested.
Data regarding pathways mediating the hypertrophic compensatory adaptation in Atrx cKO mice will also be presented.
Whether CUL4B deficiency in mice will also result in growth and mental retardation is yet to be tested.
The substantial weakness of these mice will also be very informative to evaluate a functional benefit of these therapies.
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"The assumption had been that what is true for the mouse will also be true for humans, but we now know through the work carried out by Kathy and others over the last few years that this is unlikely to be true; indeed there seem to be many differences," Professor Lovell-Badge said.
Investigating the phenotype of the knockout mouse will also be vital in identifying the key physiological and pathophysiological roles of the MG23 protein.
The CiliaGFP mouse will also be useful for studies of the brain where primary cilia in the hippocampus as well as motile cilia on ependymal cells of the ventricles have been shown to be well labeled.
A "vertical" style mouse such as the Evoluent vertical mouse will also aid in improving blood flow to your wrists.
To determine the baseline reading, untreated female FVB mice will be also be analyzed.
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