Sentence examples for mice which still from inspiring English sources
Even though no evidence supports a direct role of RPGRIP1 in the subcellular targeting of opsins, two prior studies reported the mislocalization of rhodopsin in Rpgrip1 tmiceli mice, which still expresses RPGRIP1, but without its C2 and RID domains, and Rpgrip1 nmice7 mice, which lack RPGRIP1 expression.
To test this possibility we assessed the effect of the parkinsonian neurotoxin MPTP on adult mBACtg Dyrk1a mice, which still contain relatively large amounts of Dyrk1a protein and Thr125-phosphorylated Casp9 in the ventral mesencephalon, while establishing a normal distribution of Dyrk1a in their SN.
At the longest delay tested (60 s), both SREB2 Tg and WT mice showed impaired performance compared with the SREB2 KO mice, which still performed at above random alternation (% correct: WT, 47.5 ± 5.3, n = 8; SREB2 KO, 68.6 ± 8.6, n = 8; SREB2 Tg, 37.5 ± 8, n = 8; post-hoc KO vs. WT, P < 0.05; KO vs. Tg, P < 0.05, Fig. 8B).
Somehow, the awfulness of the hockey puck mouse lasted 18 months before Jobs killed it in January 2000, citing its terrible reviews, and introducing an oval-shaped optical mouse which still – like all Apple mice before and since – only had one button.
Determination of Cnp mRNA expression in brains of young versus old mice revealed a remarkable decrease upon aging in Wt mice, which, however, still maintained levels above those in Cnp+/− mice (Fig 1K).
In order to limit antigen presentation to the cross-presentation pathway, we needed to infect non-antigen-presenting cells with a virus that was incapable of spreading to infect other cells within the mouse, but which still produced all immunogenic viral proteins.
The disputes over human embryonic stem cells that perplexed the Clinton and Bush administrations emerged from a technique developed in mice, which are still the test bed for most basic work on stem cells.
It is noteworthy that daptomycin therapy is initiated as early as 2 h post S. aureus infection in neutropenic mice, which may still be in the range of prophylactic therapies.
These tested mice (33.3% of which still survived at this time) exhibited partial dysfunction of their hindlimbs but could still perform this test.
For this reason, the present study was designed to determine if adolescent mice (3½ weeks of age), which still have relatively proliferating livers, would have differential transduction compared to older (7 weeks of age) mice.
Before we generated the Fto conditional knockout line, we had made another genetrap mouse line (Figure S1A, B) which still had residual expression of wildtype FTO (Figure S1C).
