Sentence examples for mice which only from inspiring English sources

To test whether the loss of IRF8 had a functional consequence on tumor outgrowth by acting through the loss of cDC1s rather than the expansion of granulocytes, we measured the growth of PyMT-mCh-OVA tumors in IRF8−/− mice, which lack cDC1s and have expanded granulocytes, and Batf3−/− mice, which only lack functional cDC1 (Supplementary Fig. 7c 18,41.

A group of mock-vaccinated mice which only received phosphate-buffered saline (PBS) was included as control.

Therefore, different from the POMC-GFP mice, which only labels the new-born neurons up to two weeks postmitotic, our GAD67-GFP transgene labels the whole developmental stage of newborn neurons.

To address the possibility that this increased aggregation of 2UIM ataxin-3 reflects transient overexpression in nonneuronal cells, we compared levels of SDS-insoluble ataxin-3 aggregates in whole brain lysates from aged MJD84.2 mice, which express primarily expanded Q84 3UIM ataxin-3 transprotein, and Q71B mice, which only express expanded Q71 2UIM ataxin-3 transprotein (Figure 4C and 4D).

The finding that Pbx2 was reduced to comparable extents in Pbx1NT and Prep1i/i hypomorphic mice, which only share some of the abnormalities of thymic development, suggests that Prep1 and Pbx2 might have non redundant roles and/or Prep1 might exert a Pbx2-independent function in determining the T cell fate.

In contrast to MBD2-null mice which only displayed a mild maternal phenotype as discussed above, MBD3-null embryos are severely affected at day 8.5 and die.

Likewise, unlike the Bluetooth version of the Mighty Mouse, the Magic Mouse (which only comes in Bluetooth) seems very stable and responsive (though there are varying reports on this for certain types of machines).

Furthermore, it is important to realize that the concept of colonization resistance has been demonstrated only in gnotobiotic mice (mice in which only certain known strains of bacteria and other microorganisms are present), and its relevance has never been documented in critically ill patients.

Such an embryonic lethal phenotype was not rescued in ΔT mice, however, unlike CXCR4-null mice of which only 50% survived till E17.5 and all with reduced body sizes [4], ΔT embryos were present at Mendelian ratios till E18.5 with grossly normal body sizes and morphology (data not shown).

Predictably, spontaneous tumor formation was less in heterozygous mice, in which only 6 of 31 (19%) mice showed macroscopically visible adenomas (1.5 tumors per mouse; Table S1).

Despite modest IgG and HAI titers, 5/6 of the sHA.GCN4pII vaccinated mice survived the challenge compared to sHA vaccinated mice in which only 1/6 survived (Figure 6C).