Sentence examples for mice which leads from inspiring English sources

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Similar investigations addressed the role of miR-155 in overexpressing transgenic mice, which leads to pre-B cell proliferation in bone marrow and spleen, followed by high grade B cell neoplasms [21].

The importance of MT in maintaining metal homeostasis is clearly demonstrated in studies involving exposure to heavy metals (either by diet or environment) in MT-1/2 knockout mice, which leads to metal toxicity, while MT-1/2 overexpressing mice are relatively protected from heavy metal toxicity [see review, 17].

Renin expression is highly elevated in VDR null mice, which leads to systemic hypertension, cardiac hypertrophy and heart failure [ 19].

It is important to recall that neocortical growth is abridged in ablated mice, which leads to excessive, transient local accumulations of viable GPT neurons.

We have shown that hypoxia-induced autophagy activity declines with age in mice, which leads to accumulations of damaged mitochondria and mitochondrial ROS in the kidney [ 46].

The importance of Mcl-1 in regulating neutrophil survival is revealed by myeloid specific deletion of Mcl-1 in mice, which leads to neutropaenia without any observable defects in macrophage number or function (54).

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In 1948 he received a research fellowship to investigate the effects of asphyxia and jaundice in newborn mice, which led to his interest in the prevention of cerebral palsy.

An incisor tooth phenotype was originally reported in Lrp4 mutant mice which led us to investigate the tooth development in more detail in these mice.

Excess sprouting of motor nerve terminals was also found in ephrin-A5 knockout mice, which lead us to investigate a possible link between Meltrin β and ephrin-A5-Eph signaling in the development of the NMJ.

Excess sprouting of axon terminals were also found in ephrin-A5−/− mice, which lead us to examine whether Meltrin β regulates ephrin-A5-Eph signaling in the formation of the NMJ.

Methanogenic Archaea also located in ob/ob mice, which lead to increasing of the efficiency of bacterial fermentation [ 29].

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