Sentence examples for mice which indicated from inspiring English sources

Taken together, our results demonstrated the higher GCL and GPx activities in female mice, which indicated their crucial roles in regulating the resistance of liver injury induced by hepatotoxins in female.

Two and four months after transplantation, the percentage of donor-derived T-cells and B-cells in PB and BM of ATM−/− and ATM−/− Gadd45a−/− mice was still comparable and much lower than WT and Gadd45a−/− mice, which indicated that deletion of Gadd45a has no impact on the cell intrinsic defects of immune system of ATM−/− mice (Fig. 1E and 1F).

Moreover, the expression level of PLP in the brain became comparable between 15 week-old WT and Olig1−/− mice, which indicated that the process of PLP expression to reach its optimal level might be delayed in the Olig−/− mice.

The expression of Ube3a was readily detectable and similar in liver tissues among m−/p+, m+/p−, and m+/p+ mice which indicated biallelic expression of Ube3a in non-CNS tissues (data not shown).

The results revealed that PNA-binding GC B cells clearly developed in the spleen of Gpr97-KO mice, which indicated an intact GC formation despite Gpr97 deletion.

SIRT1 upregulation, induced by CR, was also attenuated in eNOS−/− mice, which indicated that NO derived from eNOS played an important role in SIRT1 expression [ 130].

Furthermore, we also observed an increased metastasis (one case of BM infiltration and one case of spleen infiltration) in ATM−/− Gadd45a−/− mice, which indicates that Gadd45a deletion increases the degree of malignancy of lymphoma in ATM−/− mice (Fig. 5D).

We have previously shown that GNPs are capable of inducing an antibody response in mice, which indicates that factors other than cytotoxicity may be involved and complicates in vivo application of GNPs [16].

Buckbinder et al. demonstrated an increase in alkaline phosphatase activity and increased bone mineralization in bone marrow cultures from Pyk2−/− mice, which indicates that Pyk2 may be involved in the regulation of differentiating pre-osteoblasts [30].

We have carried out a series of immunogenicity and protection studies following active immunization of mice, which indicate that a whole virus, nonadjuvanted vaccine is immunogenic at low doses and protects against live virus challenge.

After T cell receptor activation, thymocytes isolated from Thy-1 null mice have increased SFK activity and cell proliferation when compared with thymocytes collected from wild-type mice, which indicates that Thy-1 inhibits T cell receptor-induced SFK activation and proliferation of thymocytes [4].