Sentence examples for mice which failed from inspiring English sources

Moreover, phenotypic correction assayed by tail clip challenge resulted in survival of all AAV1-F9 treanimalsinals, in contrast to naive mice and 50% of AAV2-treated hemophilia B mice, which failed to survive.

The CD1-restricted NKT cells in these mice, which failed to respond to alpha-galactosylceramide and which therefore were not classical type I iNKT cells, appear to represent an NKT cell subset restricted by a beta(2)m-independent form of CD1d.

This observation is in accordance with the previous descriptions of other Card15/Nod2 KO models of mice which failed to reveal gross intestinal abnormalities under basal conditions [7], [25].

This is in stark contrast to the FVB Db VP2 mice which failed to generate an antibody response to recombinant VP2.

In contrast with the human condition, the absence of Mpv17 was not associated with metabolic fragility of the Mpv17−/− mice, which failed to develop fasting-induced hypoglycemia, increased sensitivity to hepatotoxic valproate, or hypothermia by prolonged exposure to cold.

Briefly, human neonatal foreskin was engrafted onto the hind flanks of C.B.-17 scid mice, which fail to reject the xenografts.

This abnormal distribution is similar to that described in Caspr1-null mice, which fail to generate calyceal junctions (Sousa et al., 2009).

Studies in PDX-1 deficient mice (which fail to develop G-cells) demonstrated no alteration in gastric amylin expression, confirming predominant expression of amylin within D-cells [ 23].

The importance of M-CSF-induced osteoclastogenesis is confirmed in mouse models: op/op mice, which fail to express functional M-CSF, and c-fms (the M-CSF receptor) deficient mice show an osteoclast-poor osteopetrotic phenotype [ 99, 100].

Using p47-/ mice, which fail to produce oxygen radicals via NADPH oxidase, we have shown that during IFN-γ-stimulated IC-mediated arthritis, oxygen radicals completely determine chondrocyte death and aggravate MMP-mediated cartilage destruction.

Moreover, we demonstrated that pp6 cells from FoxO3 null mice, which fail to completely differentiate due to the absence of MyoD, can be rescued by T3, thus overcoming their differentiation defects.