Sentence examples for mice which display from inspiring English sources

In addition, we have used the newly engineered APPSL/presenilin 1 knock-in transgenic mice, which display a severe neuronal loss in hippocampal regions, to analyze the activation of double-stranded RNA-dependent protein kinase.

C3H/HeJ mice, which display a point mutation in the tlr4 gene that abrogates the receptor activity, were immunized through the nasal route as described for BALB/c mice.

Conversely, the present NRG1-Tg mice, which display the increases in these pathological markers, may be irrelevant to an animal model for schizophrenia in spite of their schizophrenia-like behavioral deficits.

In order to investigate the effects of Ro52 deficiency on IRF7 levels in primary immune cells, we used bone-marrow derived macrophages (BMDMs) from Ro52-deficient mice, which display enhanced type I IFN production following TLR stimulation [26].

Unlike the Mmp9−/− mice, which display aberrant cartilage formation at 10 days post-fracture (Fig. 6A bottom left panel; [5]), Mmp13−/− stabilized fracture calluses (Fig. 6A, middle left panel) did not display cartilage and were comparable to WT (Fig. 6A, top left panel).

At the molecular level, although catecholamines affect the phase of clock gene expression in the ex vivo heart [42], the rhythms of clock gene expression in the heart can be entrained to daytime feeding even in catecholamine-deficient mice, which display attenuated BP rhythms [43], [44].

Cardiac stress testing demonstrated significant heart disease in α-DB null (adbn−/−) mice, which displayed mortality and lesion sizes that were equivalent to those seen in dystrophin-deficient mdx mice.

Interestingly, bone density was considerably decreased in male TH mice, which displayed hyperglycemia.

Egr-1−/− mice, which displayed basal airspace enlargement, resisted cigarette-smoke induced autophagy, apoptosis, and emphysema.

This finding resonates strongly with the initial experiments on Rest−/− mice, which displayed embryonic lethality around E11, but importantly, showed no widespread precocious expression of Rest target genes.

These results indicate that Egr-1−/− mice, which displayed basal airspace enlargement, resisted cigarette-smoke induced autophagy and apoptosis, as well as further changes in airspace enlargement as assessed by MLI.