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This finding is consistent with the present results as we only detect a general learning factor in our mice when we examine learning at the early stages of acquisition, a point at which differences in D1 signaling seem to be involved [11]; [11].
This study revealed more differences between NTG and TG mice when we subdivided both groups per gender.
In our previous studies of these mice, when we expressed the mutation postnatally, and not during embryogenesis, we saw a progressive phenotype with several characteristics of the HGPS skin phenotype (Sagelius et al., 2008).
Indeed, acute phase response signaling was the top downregulated canonical pathway in EPA-treated old mice compared with old control mice when we performed an unrestricted pathway analysis combining RNA and protein expression together (Table 2).
That we find a differential degree of Mup transcript(s) enrichment in C57Bl/6J wild type and ob/ob mice when we use the Mup1 primer set vs. the Mup1/2 primer set suggests that within the Mup multigene family there are distinctions regarding the influence of obesity on the degree of differential expression of particular Mup transcript(s).
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You can say what you like about us, safe in the knowledge that while we slaughter babies and laugh at murdered policemen ("Tell her we're the iron fist now") we will squeak no louder than a mouse when we are abused.
In a proposed class action lawsuit, Kelley is suing to protest the practice of putting Vista-Ready on anything and everything with a keyboard and mouse when we all know damn well that a Dell with 256MB and greenscreen monitor won't show Vista's signature task switching thingy.
In mouse, when we align exon 3b with Dync1i1 genomic sequence, aligning either DNA or the translations, we are unable to detect a likely equivalent exon, thus this exon 3b appears specific for Dync1i2 in mouse and rat (and see Discussion).
For example, we observe similar enrichments in both human and mouse when we set γmax to be the smallest γ∈ Γ such that the median domain size is >80kbp (two consecutive Hi-C fragments at a resolution of 40kbp).
We use the following convention to name those mice groups: when we write Tga20→B6 mice, this means that Tga20 BM cells have been injected in B6 mice for hematopoietic reconstitution.
This method was modified based on our previous work with insulin-sensitive df/df and GHRKO mice (26) when we observed that subjecting these mice to 4-h fasting before ITT caused glucose levels dropping below 20 mg dL−1.
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