Sentence examples for mice when performed from inspiring English sources

Remarkably, a single administration of LV-FIX targeted for expression to hepatocytes strongly reduced anti-FIX Abs and eradicated inhibitors in 75% of the treated mice, when performed both at the time of development or during ongoing anti-FIX immune response.

Prior preclinical studies have shown that both active and passive immunotherapies were effective in lowering plaques in transgenic APP mice when performed as a preventative treatment; however, when performed as a therapeutic approach in aged transgenic mice, they lacked any effect on plaque levels [ 15, 50].

Indeed, acute phase response signaling was the top downregulated canonical pathway in EPA-treated old mice compared with old control mice when we performed an unrestricted pathway analysis combining RNA and protein expression together (Table 2).

In inducible disease models, protective as well as therapeutic effects of HSCT were observed: both syngeneic and allogeneic HSCTs in EAE-susceptible mice protected animals from disease when performed close to immunisation, but only allogeneic HSCT with high-grade chimerism was effective in protection against EAE when the time lag was longer.

Also, the usually safe 66% LR in healthy mice is plagued with significant lethality when performed on livers with underlying metabolic disease, such as in PPARα-/ and Leptin or Leptin-receptor deficient mice [13], [14].

Similar results were obtained when performed with WT mouse splenocyte lysates (data not shown).

10 21 26 Such findings underscore the importance of clearly defining mouse background strain when performing α-defensin studies.

This mechanism is supported by the observation that in utero PFOA exposure did not affect weight gain in the previously mentioned study on CD-1 mice when ovariectomy was performed in exposed offspring after delivery (Hines et al. 2009).

When performing studies in mice the unique anatomy hampers the results: the mouse pancreas consists of three lobes, a gastric, splenic and a duodenal lobe, which drain their juice via individual ducts.

Improper wrist position when performing an activity (holding a computer mouse, for example).

When performing, smile.