Exact(21)
ApoE KO mice, a well-established animal model of atherosclerosis, had higher expressions of KLF14 in aorta tissues than that in C57BL/6 J mice when fed the high-fat diet (HFD) or standard chow diet.
OPN KO mice were protected from HFD-induced hepatic and skeletal muscle insulin resistance and had greater hepatic insulin sensitivity than WT mice when fed NC.
As shown in Fig. 2A (left panel), plasma PLTP activity in LDLR−/−/huPLTPtg/wt mice were approximately 3-fold higher than in LDLR−/− mice when fed a chow diet (0 weeks).
For all strains, mutant mice have higher serum bilirubin levels than WT mice when fed cholate diet (p<0.001); after consumption of control diet, the effect of genotype is significant only for the 129 strain (p<0.05; Figure 4).
The data also shows that, consistent with previous work [7], RIZ1+/+ mice had lower mortality and tumor incidence than RIZ1−/− mice when fed methyl-balanced diet 1 (Figure 1C).
As a result, ObRb SERT-/ mice, when fed a normal diet, developed an obesity phenotype.
Similar(39)
To prevent this from happening to your scaly pal, be sure to pick them up some frozen thawed mice when feeding time comes around!
BALB.apoE-/ mice have much higher HDL cholesterol levels than B6.apoE-/ mice, especially when fed a high fat diet, although their non-HDL cholesterol and triglyceride levels are comparable [ 16].
However, the TG mice did not develop impairments in insulin sensitivity and glucose tolerance like the WT mice did when fed the HFD for 7 weeks.
We did not detect significant differences in food intake in Eps8KO mice, either when fed on normal chow or on a high fat diet (Fig. 3A).
This effect has been recapitulated in B6 mice, which when fed an HFD have a TCDD elimination half-life 2.4 and 1.4 times longer in liver and adipose, respectively, compared with those on a normal diet (DeVito et al. 2003).
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