Sentence examples for mice were ventilated from inspiring English sources

To induce VILI, mice were ventilated with HVt ventilation of Vt 25 mL/Kg, respiratory rate 50 bpm and PEEP of 2 cmH2O for four hours.

Untreated wild-type mice, IL-1αβ knockout and caspase-1 knockout mice, pralnacasan (a selective caspase-1 inhibitor -treated minhibitor -treatedcyte-derived chemicene (KC)-treated mice and cyclophosphanti-keratinocyte-deriveddepleted wild-type mice were ventilated using clinically relevant ventilator settings (tidal volume 8 ml/KC -treated

After preparation, a recruitment maneuver was performed (increasing of the airway pressure to 30 cmH2O), and mice were ventilated for 4 hours with the following ventilator settings: Mice were ventilated with a tidal volume of 9 ml/kg, respiratory rate of 160 per minute, and I E ratio of either 1 2 or 1 1 (LVT 1 2; LVT 1 1).

In a separate series of experiments, anesthetised and tracheostomised mice were ventilated with a custom-made mouse ventilator (8 9 ml/kg tidal volume, 2.5 cmH2O positive end-expiratory pressure (PEEP), respiratory rate 120), with a carotid arterial line inserted for blood sampling, fluid infusion (0.4 ml/hr saline containing 10 U/ml heparin) and monitoring arterial blood pressure [16].

Adult male wild-type and Tpl2-deficient mice were ventilated with normal or high tidal volume for 4 h.

Healthy wild-type (WT) and RAGE knockout (KO) mice were ventilated with relatively low (approximately 7.5 ml/kg) or high (approximately 15 ml/kg) tidal volume.

However, we have previously shown that the inflammatory response is aggravated when mice are ventilated with these parameters for a longer period of time or when higher tidal volumes are used, suggesting that the inflammatory response is mainly ventilation-induced.

To assess the physiological relevance of MMP8 in VILI, mmp8 gene deleted mice (mmp8−/−) were ventilated and their lung injury parameters were compared to wild-type mice.

In the first study [ 10], wildtype or c-jun N-terminal kinase (JNK -deficient knockout mice (JNK -deficientventilated with high Vt (30 mL/knockout two different fractions of inspired oxygen: 21% O2 (roomicer) or greater than 95% O2 (hyperoxia).

Healthy C57Bl/6 mice (n = 66) or BALB/c mice (n = 66) were ventilated (tidal volume = 7.5 ml/kg or 15 ml/kg; positive end-expiratory pressure = 2 cmH2O; fraction of inspired oxygen = 0.5) for five hours.

BALB/c mice (n = 84) were ventilated for 5 hours with low (7.5 ml/kg) or high (15 ml/kg) tidal volume, a positive end-expiratory pressure of 2 cmH2O and a fraction of inspired oxygen of 50%.