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Without adenosine receptors, the mice were unable to respond to the adenosine released when cells were damaged by acupuncture needles.
However, Ast-Tbr2DN mice were unable to upregulate TGF-β1 and its activator thrombospondin-1 2 days after dMCAO.
As a consequence of these disruptions these mice were unable to successfully complete the VOR phase-reversal paradigm (Fig. 7b).
Additionally, MCHAtax mice were unable to consolidate SWS and increase slow-wave activity (SWA) in response to this homeostatic challenge as observed in MCHWT littermates.
The researchers found that the Clock mice were unable to control their weight, regardless of which diet they were on.
During that time, the mice were unable to move or turn around in the tube.
Exhaustion was defined when mice were unable to avoid repetitive electrical shocks.
In grip strength tests, the Mariusz mice were unable to grip effectively.
Their lifespan (endpoint) was determined by the observations that mice were unable to move by themselves.
Kb+/+Db+/+ mice were unable to reject Kb+/−Db+/− cells to any measurable extent (Figure 2A).
In contrast to wildtype mice, cIAP-1 KO mice were unable to resolve the infection.
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CEO of Professional Science Editing for Scientists @ prosciediting.com