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Other sporadic findings, which are common in aged mice, were small foci of hepatocellular necrosis, vacuolation of and degeneration/regeneration of kidney tubular epithelial cells, mineralization in the kidney tubules in the pelvis and cortico-medullary junction (not shown).
As shown in Fig. 4B, whereas well-developed labyrinthine layers with obvious villi were present in E9.5 EpCAM +/− placentas, placentas from EpCAM −/− mice were small, the labyrinthine layer was thin and villous formation was limited.
At 10 days after TM treatment, i.e., soon after the acquisition of the Ate1−/− genotype, the differences between distances travelled by Ate1-deficient versus Ate1-containing mice were small (Fig. 8A).
KO mice were small, as LBM was 77% of normal.
Lexicon's KO mice were small and sickly with death occurring about 3 weeks of age.
Few dysplatic lesions found in RAGE−/− mice were small and low grade (data not shown).
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Cardiomyocytes from adbn−/− mice were smaller and responded less to adrenergic receptor induced hypertrophy.
On arrival, all of the apoE−/−mice had similar weights, but by the time of study, the diabetic mice were smaller than the non-diabetic mice with average weights of 23.1 ± 1.2 and 30.7 ± 1.1 g (P = 0.0001).
Size of bbee mice were smaller than wild-type (BBEE) mice; and their hair was rough (Figure 1A).
These mice were smaller, possessed smaller and paler kidneys, were proteinuric and died between 3 24 weeks of age.
However, we observed that DLC2-deficient mice were smaller and had less adipose tissue than the wild type mice.
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