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Dox-encapsulating aptamosomes administered to LNCaP xenograft nude mice were selectively retained in tumor tissue.
To investigate neurobiological correlates of trait anxiety, CD1 mice were selectively bred for extremes in anxiety-related behavior, with high (HAB) and low (LAB) anxiety-related behavior mice additionally differing in behavioral tests reflecting depression-like behavior.
Harvested spleens from immunized transgenic mice were selectively depleted of CD8+ or CD4+ T cells by use of anti-CD8 or anti-CD4 antibody-coated immunomagnetic beads with LD columns (Miltenyi Biotec, Auburn, CA) according to the manufacturer's protocol.
To make use of the advantages of the full spectrum of molecular-genetic approaches, CD1 mice were selectively inbred for either low or high anxiety-related behavior in analogy to the HAB/LAB rat model, while maintaining a high degree of similarity in non-selected traits.
For this purpose, tumour-bearing mice were selectively depleted of either NK cells, neutrophils, macrophages or all three cell types combined.
Three closed lines of mice were set up, two experimental lines (the Longshanks mice) in which mice were selectively bred (Lines 1 and 2), and one control line in which mice were bred at random (Line C).
Similar(54)
Thus, the results of the fear conditioning test shown in Fig. 1 suggest that the contextual fear conditioning in SCR mice was selectively impaired.
Ruan et al. also found that striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to MC II III inhibition [32].
MN loss in Mag-null mice was selectively increased in larger-sized MNs with respect to Wt mice.
This hypothesis is supported by our previous findings, showing that Tc1 mice are selectively impaired in short-term memories when tested in different behavioural tasks (23, 27).
The oral region (snout) of female C57 black mice was selectively irradiated with 225 kV X-rays (HVL 0.5 mm Cu, dose rate 0.7 Gy min−1 at 25.5 cm from the target, 250 kV Phillips).
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