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In this study, it is possible that hypoxic cells in the tumours were induced, because the tumour volumes of the mice were relatively large.
Jnk1−/− mice were relatively resistant to VILI, and their global gene expression patterns differed from that of wild-type mice.
Interestingly, we observed much higher levels of serum IL-2 in Jak2−/− mice although IL-2 levels for both Jak2−/− and control mice were relatively low (Figure 4C).
Our results show that mechanical ventilation resulted in increased alveolo-capillary permeability and subsequent pulmonary edema formation in mkk3−/− mice, whereas jnk1−/− mice were relatively resistant to alveolar fluid accumulation when compared to wild-type mice.
A previous report showed that a reduced number of CD4+ T cells in the thymus and periphery of cathepsin L deficient mice was observed, and that CD8+ T cells in the deficient mice were relatively increased [29].
All other immune parameters in the surviving mice were relatively low and similar to previous days.
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A model based on the Generalized Matching Law indicated that sensitivity to reinforcer magnitude was lower for MeHg-exposed mice relative to controls, indicating that responding in MeHg-exposed mice was relatively indifferent to the larger reinforcer.
The stathmin knockout mice are relatively fearless.
We have observed that Stx-t−/− homozygous mice are relatively pale.
Rodents offer many advantages for investigating these relationships, as they are appropriate for a wide variety of experimental techniques and genetically modified mice are relatively easy to obtain or produce.
Altogether, our findings indicate that while operant performance for food in mice is relatively insensitive to many study parameters, experimental outcomes can be shaped predictably with proper design decisions.
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