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None of the genes identified as HFD-regulated in DMBA-treated mice were regulated by HFD in the absence of DMBA.
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Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue.
FMO3 expression in mice is regulated by sex hormone, repressed by androgens and stimulated by estrogens (Bennett et al., 2013).
We recently have shown that gene expression of miR-433 and miR-127 in mice was regulated via a nuclear receptor ERRγ/SHP dependent mechanism [4].
The development and patterning of cone cells in mice is regulated by the nuclear receptor thyroid hormone receptor β2 (Trβ2, Nr1a2b), which controls the dorsal-to-ventral development and the terminal differentiation of medium (M -opsin expressing cone cells [6]–[7].
To test the hypothesis that the increase in PAI-1 transcription observed in CAPs exposed mice is regulated by TNF-α, we treated mice with the TNF-α inhibitor, etanercept (10 mg/kg, 3 days before and on the first day of exposure to CAPs).
Similarly, immunity to dermal and disseminated candidiasis in mice is regulated by the IL-17 pathway [ 18, 19].
LacZ expression in the Ildr1+/− mice was regulated by the promoter of Ildr1, and this allowed the ILDR1 expression pattern to be determined by measuring β-galactosidase activity.
Thus, hepatocellular injury from STZ in mice is regulated by cFLIP and involves both acute toxicity and metabolic mechanisms that occur only in vivo.
IPA revealed that some of the genes dysregulated in both humans and mice are regulated by insulin signaling (Figs 3 and 4 B).
Other studies indicated that the cell accumulation and inflammation seen in MRL/ lpr mice is regulated by IFN-γ receptor signaling pathway [ 32].
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