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Indeed, longitudinal BLI changes in individual mice were readily approximated as exponential (R 2 > 0.9) in all but one mouse in treated group and one mouse in control group, which allowed for calculation of BLI "doubling time" as a surrogate parameter for changes in metastatic burden.
However, spontaneously driven Ca2+ transients in acute brain slices from transgenic mtGA newborn mice were readily detectable.
However, T-cell infiltrates in nonobese diabetic mice were readily detected in the pancreas [ 16].
Preliminary investigations established that, at this time, the amount of synaptic degeneration in muscles from WldS and WT mice were readily distinguished.
Comparing the two chow diet groups, ob/ob mice were readily separated from control animals using O2PLS-DA (R(X) = 71.8%; R(Y) = 99.8%; Q = 96.4%; Fig. 4b).
Similarly, extracts of cerebellum tissue from mdx mice were readily distinguished from wild-type controls by their metabolic profiles, including a characteristic increase in phosphocholine.
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We show that mice are readily susceptible to avian H5N1 influenza virus infection, and that mice with overexpression of Hdac6 show enhanced resistance to H5N1 virus, as demonstrated by postponed death, reduced death rate, and body weight maintenance.
In contrast, outbred mice are readily available, relatively inexpensive and standard phenotyping protocols can be used without modification.
The spread of HSV-2 MS-luciferase from the vaginas of naïve and gD-2-immunized mice was readily visualized between Days 2 and 6 post-challenge (Fig. 6A).
The Ppt1-activity in the heterozygous mice was readily detectable, albeit lower than that in WT mice (Fig. 2C).
In contrast, free ICG in mice is readily distributed into the blood with a lower image resolution.
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