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Tumor-bearing mice were randomized into treatment groups, when necessary.
A total of 12 mice were randomized into 4 different groups.
When the volume of xenografts reached approximately 100 mice mice were randomized into groups and treatments initiated.
Once tumors grew to a palpable size (~ 500 mice, mice were randomized and treated daily with 20 mg/kg (body weight) PLX4720 via intraperitoneal injection.
Upon establishment of tumors (150 250 mice, mice were randomized into two groups: vehicle (0.5% methylcellulose, 4% HPMC-AS) or NB-598 (300 mg kg−1).
Sixty female inbred BALB/cJ mice were randomized into six tibial nerve transplant groups, including three isograft and three allograft (C57BL/6J) groups.
Once tumor xenografts were established, mice were randomized into study groups and the treatment was initiated.
When mean tumour sizes reached approximately 0.2 cmicemice were randomized into control and treatment groups.
When the tumor volume reached approximately 80 mm3, the mice were randomized into the experimental groups.
We established a SW620 xenograft mouse model and mice were randomized to six groups with different treatment strategies (Fig. 4A).
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Diabetic and non-diabetic ApoE−/−/AT1R−/−-mice were randomized to receive either GW9662 or vehicle.
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