Genetically engineered mice are particularly powerful models to identify the specific cells, genes, and pathways that regulate initiation and progression of pancreatic cancer.
These autophagy-deficient PEPCK-Atg7−/− mice are particularly vulnerable to cisplatin- and ischemia-reperfusion induced acute renal injury, suggesting potent renal protection by ATG7-mediated autophagy (Jiang et al., 2012).
The leanness of Ate1-deficient mice was particularly striking in view of their hyperphagy (see below).
Generation and expansion of MSCs from C57BL/6J mice is particularly difficult and time-consuming.
In the present study, we have shown that early-adolescent B6 mice are particularly motivated to approach conspecifics, and while doing so, produce USVs at a high rate.
Within B cell populations, the proportion of the CD11b+CD23− B-1 cell subset in TRAF6-ΔB mice was particularly affected, with the proportion of CD11b−CD23+ B-2 cells being correspondingly higher (Fig. 8b, middle panels).
Nevertheless, the test is discussed here because previous data from our group revealed that corticosterone level in Ind mice are particularly sensitive to the acute exposure to an open field [33].
Amyloid deposition in FDD-Tg mice is particularly strong in the cerebellum (Fig. 4e) but not in Knock In mice (Fig. 4b) and only FDD-Tg mice showed immunoreactivity using Ab 1700, specific for the ADan amyloid peptide [20] (Fig. 4f versus 4c).
