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Control mice were orally administered saline instead of lovastatin.
Neonatal hUGT1 mice were orally treated with DHA.
Briefly, mice were orally administered with FITC-dextran (60 mgm100 gm body weight).
Neonatal hUGT1 mice were orally treated with linoleic acid (LA) and oleic acid (OA).
Neonatal hUGT1 mice were orally treated with oleic acid and linoleic acid (10 g/kg).
For infectivity experiments, mice were orally inoculated with saline or 109S.
As a positive control group, mice were orally administered donepezil hydrochloride (0.5 mg−1 kg−1 day−1; Wako Chemicals, Osaka, Japan).
The model mice were orally treated with DHA (10 mg/kg) at 12 days after birth and their bilirubin levels were measured at 14 days after birth, 48 hours after the treatment.
To perform OGTT, overnight-fasted mice were orally administered with HBK001 (at the indicated doses) or linagliptin (2 mg/kg) 1 hour prior to oral glucose load (2 g/kg).
The mice were orally administrated with RJ extract (16, 32 or 64 mg(kg−1) daily for consecutive7 days before LPS challenge.
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After 2-weeks from final inoculation the mice were orally-fed with curcumin (25 mg/kg or 50 mg/kg b.w).
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