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HDC−/− mice and H1R−/−/H2R−/− mice were of a genetic background of a C57BL/6 J strain, and their littermates were used as wild-type (WT) controls.
All mice were of the strain background C57Bl/6;129X1SvJ.
The mice were of a mixed C57BL/6J and 129SvJ background.
In our experiments, control mice were of either the genotype Adam17flox/+ or Adam17flox/flox (without Foxn1-Cre).
All mice were of similar genetic background (≥90% C57Bl/6, ≤10% FVB/n) and maintained as heterozygotes.
The two groups of mice were of similar initial body weight, with no significant difference in body weight in the first 13 days after rAAV injection (Figure 1C).
Similar(14)
Outside the city, however, rats (and mice) are of some ecological benefit.
A minority of WT mice was of pure strain stock, rather than derived from backcrossing.
At two months, AC3−/− and AC3+/+ mice are of comparable weight.
In this context, genetically modified animals, especially several knockout mice are of greatest interest.
The histological findings of arthritis in the Pep-injected NMRI-mice were of moderate severity.
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