Sentence examples for mice were modestly from inspiring English sources

DOI: http://dx.doi.org/10.7554/eLife.02669.010 Nestin-Cre; Bmi-1 fl/fl mice were modestly but significantly smaller than littermate controls.

Interestingly, activated B cells from bim−/− bad−/− mice were modestly, but significantly (p<0.05), more refractory to cytokine deprivation than bim−/− cells.

By three weeks after birth the growth rate of Lrp4 −/− ; Lrp4 m mice began to slow and by 6 weeks the mice were modestly runted.

The greater than 50% reduction in Lrsam1 transcript in heterozygotes might indicate some autoregulatory feedback mechanism and also suggests that the dosage dependence of the severity of the Lrsam1 phenotype is not a simple linear relationship with LRSAM1 levels, although protein levels in heterozygous mice were modestly reduced, as anticipated.

In our colony, disease progression in these mice was modestly delayed (by a few weeks) as compared to what was reported by Wang et al, [4](Table 3), the PBCre4×Ptenflox/flox mice developed invasive carcinomas and adenocarcinomas at a time when the ARR2PBCreER(T2)×Ptenfl/fl mice treated with OHT at 2 wks of age, were starting to develop microinvasive carcinomas.

We observed that glucose uptake into hindlimb skeletal muscles from the knockin mice was modestly, but significantly (∼12%) lower than from the wild-type littermates.

The expression levels in all three transgenic mouse lines are similar but the expression in M20 αS mice is modestly higher than for the M83 αS mice, while the expression in M47 αS mice is slightly lower [ 54, 64].

We recently reported that primary chondrocytes derived from Egfr wa5/+ mice shows a slightly decrease in extracellular signal-regulated kinases (ERK) phosphorylation after being treated with epidermal growth factor (EGF) compared to WT cells, suggesting that the EGFR activity in chondrocytes from Egfr wa5/+ mice is modestly suppressed.

Real-time RT- PCR analysis showed that the level of GC-C expression in the distal colon of GC-C+/+ mice was modestly elevated at 10 p.i.. Production of GN, the most abundant colonic ligand of GC-C, was substantially decreased beginning at day 4 of infection in both genotypes, although this was significantly greater in infected GC-C−/− mice relative to infected wildtype animals.

In agreement with this notion, MYC transcripts in mice lacking MYC-335 were modestly reduced.

Thus, the levels of both of these RAP-dependent receptors were modestly reduced in mice partially deficient in RAP.