However, near the developing CA3 area, Reelin is highly expressed, both in the hilar region at E16.5 and in the lateral CA3 area at E18.5 in both wild-type and compound EphB1/2-deficient mice, excluding the possibility that the described CA3 heterotopia in EphB1/2-deficient mice is merely caused by a reduction in Reelin expression or signaling.
Writer overhears a woman ask the same question he would ask, "Once they start doing mice, who's to think they're going to stop there?" A new mouse is merely an interesting beginning, a foot in the door.
The mouse was merely a tool to build the thrilling universe he had just demonstrated, in which computers were harnessed to make people think and work faster, more effectively and more collectively.
Others were merely cryptic.
They were "merely" hungry.
These experiments formally demonstrate that different components of cognition in humans and mice are not merely analogous, but homologous, sharing common descent and genetic constitution.
Interestingly, epidermal skin cells of the stratum spinosum layer showed strong Sftpd expression in E17.5 wildtype (Fig. 7C), but not E17.5 Creb1−/− (Fig. 7D) mice, suggesting that lack of Sftpd expression in Creb1−/− mice is not merely a secondary outcome of relative lung immaturity.
Even the best "travel" mice out there are merely small, not flat, and if space is a premium for you, this mouse outdoes all comers in economical design.
Whether these mechanisms drive aging in general, are specific to the mtDNA mutator mouse model, or are merely secondary consequences of aging are important questions to be addressed in future work.
It is also important to note that the respiratory defect in Creb1−/− mice is unlikely to be merely a secondary outcome of general developmental retardation or arrest.
