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In parallel, fluorescence in situ hybridization (FISH) with Oxtr gene probe also revealed that the numbers of Oxtr mRNA-positive cells in the CA2 and CA3 of Oxtr −/− mice were markedly reduced compared with WT mice (Fig. 2d, e), confirming the efficiency of Cre-loxP-mediated deletion of Oxtr.
In a nude mice model, metastatic lung tumor nodules in HPV 18 E6-positive GNM or HPV 16 E6-positive TL-1 injected TL-1 injectede markedly decreased inudeth cell types with E6 knockdown, FOXmicenockdowereor treatmarkedlyh FOXM1 inhibitor (thiostrepton).
At five weeks post-infection, the spleens of wild-type mice were markedly enlarged.
The memory performances of mutant mice were markedly decreased only following the administration of anticholinergic antagonist, scopolamine.
Mean body weights of both treated and untreated db/db mice were markedly higher than db/+ controls at baseline (Figure 1d).
Strikingly, CD25+ cells in Lck or Lck/Fyn mice were markedly enriched for high expression of Ly-6C and low expression of CD103 (Figure 7B).
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The development of repetitive behavior in C58 mice was markedly attenuated by rearing these mice in larger, more complex environments.
injection of morphine (5 mg/kg) observed in wild-type mice was markedly reduced in opt heterozygote mice.
We have shown that methionine metabolism in Ames mice is markedly different than in their wild type littermates.
The phenotypes of the three ERR-null mice are markedly different and range from embryonic lethality for ERRβ-null mice, death shortly after birth for ERRγ-null mice, and viability for ERRα-null mice43,49,57.
Covering the surgery site by drug-loaded AMPN mat after tumor resection, in both subcutaneous and orthotopic HCC model in mice, the recurrence of HCC was significantly retarded and the survival time of mice was markedly prolonged.
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