Some obesity researchers, though, say there may be other reasons that the mice were less fat.
When the histone modification was chemically blocked, the mice were less likely to become addicted.
KO mice were less physically active than WT in cages with or without running wheels.
VTA and nAc neurons in KI mice were less affected by ethanol supporting the idea that these brain regions express α1 subunits.
The genetically modified mice were less anxious than the normal mice and were more resilient in the face of social stress.
In the EPM test, db/db mice were less anxious as observed by increased percent open arms time and entries.
They found that the mice were less likely to forage as far in lighted areas than in areas kept dark, eating at fewer of the trays within about 15 feet of the lights.
When cultured in FMS-like tyrosine kinase 3 ligand (Flt3L), we found MPs, MDPs, and CDPs isolated from tumor-bearing mice were less able to differentiate into cDC1s compared to those cells isolated from tumor-free mice (Fig. 3b).
But the mice were less helpful on this point; their teeth are so different from humans' that the researchers could not see any specific change.
At the same time, adenosine receptors in the mutant mice were less active.
Extensive necrotic areas were observed in tumors from 3TSR-treated mice, whereas tumors from gemcitabine and combinatorially treated mice were less necrotic than control tumors.
