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No strains of mice were generally sensitive or resistant to intoxication across tasks.
COX-1 had long been considered the 'housekeeping' cyclooxygenase, and therefore it was surprising that these null mice were generally healthy, displaying no immediately obvious pathology.
First, they found that the cancerous liver cells in their mice were generally accompanied by cells that had the symptoms of old age (they had, for example, stopped replicating).
TPH2KO and DKO mice were generally normal in appearance and in many of the behavioral tests employed in this study.
Basic properties of the mossy fiber synaptic transmission in the mutant mice were generally normal except for slightly reduced frequency facilitation.
HDAC4ΔC mice were generally normal at 2 4 months of age except for a strong reduction in response to a thermal nociceptive stimulus.
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Laboratory mice are generally euthanized using CO2.
All 128 Hdac6 tg mice are generally healthy, with the exception of only one mouse showing abnormal neck growth.
Nevertheless, the spatial contrast sensitivity (optokinetic response) of Cacna1fnob2 mice was generally similar to that of wild type mice.
In contrast, engraftment in MRL mice and 129SvJ mice was generally in the range of 10 35% by day 28.
LRRK2 mice are generally unremarkable with no obvious behavioral abnormalities, and no differences in body weight or survival compared to their non-transgenic littermates up to 24 months of age (data not shown).
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