Sentence examples for mice were depleted from inspiring English sources

C57BL/6 mice were depleted of CD4+or CD8+, or both, by monoclonal antibody injections and subsequently infected with C. abortus.

The mice were depleted of serotonin via two approaches (1) use of p-chlorophenylalanine (pCPA) to pharmacologically inhibit tryptophan hydroxylase (Tph), a rate-limiting enzyme in serotonin biosynthesis and (2) genetic knockout of the Tph2 isoform.

FoxP3DTR mice were depleted of their FoxP3 by treatment with DT as described previously [69].

Control mice were depleted with an irrelevant mAb of the same isotype.

Next, J8-DT immunized BALB/c mice were depleted of CD8+ T-cells and were subsequently challenged with M1 GAS.

In some studies, post immunization, mice were depleted of CD4+ or CD8+ T-cells prior to challenge with GAS.

Additionally tele-methylhistamine, the major histamine metabolite in the brain, that was initially present at a higher level in the brain of H3R−/− mice was depleted more quickly post-infection in H3R−/− mice as compared to wild-type counterparts.

Indeed, when mice are depleted of macrophages and challenged with B. anthracis spores, the animals have a shorter mean time to death than those with a normal compliment of macrophages [1].

Because most AGT in livers of DEN- or LPS-treated Alb-creGSNORf/f mice was depleted, AGT activity in hepatocytes is most likely depleted in the mice.

The endogenous gut microbiota of 6 week old mice was depleted by treating with a single dose of streptomycin (Sigma-Aldrich, St . Louis MO).

Interestingly, when wild-type mice are immunized with heat killed Listeria monocytogenes (HKLM), protective immunity is not conferred in them, but a higher level of protection is rendered if the mice are depleted in CD4 cells [ 60].