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In contrast, when fibrate-treated mice were concomitantly injected with SB225002, neutrophil counts, leukocyte- and exudate-associated bacterial loads were comparable to untreated controls (Fig 5B and D).
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Similarly, a diffusion tensor imaging animal study showed that mice that were concomitantly treated with an antipsychotic and cuprizone, a copper chelator that induces oligodendrocyte loss and demyelination, showed an attenuation of the cuprizone-induced white matter changes compared with mice receiving cuprizone alone (Chandran et al., 2012).
Cheng et al. used integrative genome-wide scans to identify genes that were concomitantly hypermethylated in mouse and human gastric cancer samples infected with H. pylori.
Immunohistochemistry analysis of mouse knee sections of surgically induced OA and sham control (with Osteoarthritis Research Society International scores of 5 and 0, respectively) revealed that phosphorylated LKB1 and AMPKα were concomitantly decreased in mouse OA knee cartilage, compared with the sham control.
Tumor formation was also not observed in mice in which both Rb and Brca1 were concomitantly inactivated via intrabursal injection of AdCre.
Notably, BLIMP1 (expressed from 6.5-dpc mouse PGCs) was concomitantly upregulated, whereas STELLA expression (expressed from 7.5-dpc mouse PGCs) was not significantly altered.
Parental cells were concomitantly transfected with the empty pcDNA3.1 vector.
Patients (61.7%) were concomitantly treated with corticosteroids.
Some of the animals were concomitantly treated with the proteasome inhibitor bortezomib and effects compared with ascorbate-supplemented Gulo, untreated or nitrate-tolerant wild-type mice.
As would be expected, Aβ38 levels were concomitantly increased [ 28].
Bronchoscopy showed bronchial inflammatory signs; mucopurulent secretions were concomitantly observed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com