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Because they lacked fur, the mice were amenable for topical application of compounds.
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It has been therefore hypothesized that the RTT-like phenotype exhibited by Mecp2 null mice is amenable of modulation by utilizing stimuli capable of eliciting neural plasticity.
In comparison, mice are amenable to genetic manipulation, and ApoE-deficient and LDL receptor-deficient mice are susceptible to atherosclerosis.
This motivates the question of whether heterozygous DO mice are amenable to classical and pharmacologically validated biomedical behavioral tests.
These data are consistent with the normal anxiety-related behavior previously described for SynI−/−, SynII−/− and SynIII−/− mice [26,32] and suggest that Syn KO mice are amenable for further analysis of their social behavior.
The mouse is amenable to many motor function tests.
Thus, although the deer mouse is amenable to laboratory life, its biology has not been purposely altered by generations of inbreeding or artificial selection.
While much of our insight regarding macrophage functional subtypes has been garnered through elegant studies in mice, which are amenable to genetic manipulation, far less is known about such cells in human tissues, and particularly in the brain under normal, disease, or injurious conditions.
Taken together, these data suggested the intriguing possibility that the severe kidney disorder in Phb2 pko mice may be amenable to a therapeutic intervention with mTOR inhibitors.
Not all of them were amenable.
Some challenges were amenable to improvement.
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