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Further, Akt/GSK3/cyclin D1 signaling pathways in the liver of treated mice were altered, which may help prevent homocysteine-induced cell cycle dysfunction.
These results show that anxiety-related behaviors of SCR mice were altered.
In cortex, 566 (wildtype mice) and 623 (APP23 mice) spots were altered and in hippocampus, 571 (wildtype mice) and 672 spots (APP23 mice) were altered, respectively.
Also, morphologies of dendritic spines in APP23 and deltaE9 mice were altered differently.
In contrast, abundance of only 201 proteins (108 up and 93 down; over 60% less proteins that are altered during ageing of WT mice) were altered during ageing of Casp2 −/− mice.
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These results suggest that 5-HT signaling in the brains of patDp/+ mice is altered during these developmental stages.
One hypothesis is that the PrPC expression pattern in Tga20 mice is altered due to the deletion of the large intron from the PrP gene construct.
In contrast, at 8 10 weeks of age glucose tolerance in both male and female dmpk−/− mice was altered (Fig. 3 B and C, respectively).
It would be interesting to determine whether cataract development in αB-R120G knock-in mice is altered in mouse strains that have the full complement of the beaded filaments.
Collagen fibres in COMP-deficient ApoE-KO mice are altered in size.
One factor that may contribute to the impaired cognition of Myk/+ mice is altered neuronal excitability.
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