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To determine whether repeated TNF injections suppress T cell function in adult mice, we studied the responses of influenza hemagglutinin-specific T cells derived from T cell receptor (HNT-TCR) transgenic mice.
To understand the behaviour of AMP-QDs in living mice, we studied their blood clearance and tissue biodistribution following intravenous administration to BALB/c mice with a dosage of 0.4 nmol per mouse.
Because muscle triacylglycerol (TAG) accumulation might contribute to insulin resistance in leptin-deficient ob/ob mice, we studied the acute (60- to 90-min) effects of leptin and insulin on [14C]glucose and [14C]oleate metabolism in muscles isolated from lean and obese ob/ob mice.
Here, with TRPM8-deficient mice, we studied whether TRPM8 in the skin induces behavioral and autonomic responses to warm skin against room cooling.
To obtain evidence for a functional role of these polymorphisms in contributing to different levels of AVP expression in male and female LAB vs. HAB mice, we studied the activity of each allele in an F1 intercross.
To determine whether NMDA receptor neurotransmission is affected in the EphA5-functional knockout mice, we studied the amplitude of NMDA EPSCs in CA1 pyramidal neurons in hippocampal slices from EphA5-functional knockout mice and matched wild-type mice on postnatal day 6.
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Given that TH expression promotes the beta cell differentiation programme, as evidenced by the pancreatic phenotype of the TH-deficient mouse, we studied the pro-beta cell effect of catecholamines in vitro.
To investigate the effect of the lack of RhoE expression on mice viability, we studied the progeny resulting from heterozygous mice crossings.
In their experiments DBA/2 mice died of a progressive systemic infection, but the BALB/c.D2Nramp1 congenic mice that we studied did not die of infection.
Using neurabin knockout (KO) mice, here we studied the function of neurabin in hippocampal synaptic transmission, plasticity and behavioral memory.
Because we observed gradual redistribution of the majority of centrosome marker proteins onto the nuclear surface in differentiating myoblasts from mice [8], we studied the potential mechanisms of altering centrosome protein localization.
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