Sentence examples for mice we generated from inspiring English sources

To investigate the role of circulating BM-derived microglia in rd7 mice, we generated rd7/rd7 Tg/Tg double homozygotes via a two-generation outcross-intercross series.

To ensure that the disruption of collagen X function rather than presence of strain specific modifiers caused the variable skeleto-hematopoietic phenotype in the collagen X Tg and KO mice, we generated congenic Tg and KO lines by backcrossing greater then twelve generations into C57BL/6 and DBA/2J strains.

First, transgenic mice we generated display a high-bone-mass phenotype, whereas transgenic mice previously reported show an osteopenic phenotype.

To investigate the effect of the αB-R120G mutation in mice, we generated αB-R120G knock-in alleles (Fig. 1A D).

To assess whether the "Leu3p-α-IPM" expression system is functional in mice, we generated transgenic mice expressing Leu3p ubiquitously under the control of the SV40 promoter (L3).

As the MDM2 expression pattern in normal tissues is similar in humans and mice, we generated TCR transgenic mice to study tolerance mechanisms against this TAA.

By crossing mice carrying this allele to the Cre deleter mouse, we generated mice that were homozygous for loss of the first Tln2 coding exon (Tln2ko/ko).

To understand the function of Pten in regulating SSC fate and fertility in male mouse, we generated conditional Pten knockout males using germ cell specific Cre strain, the Stra8-Cre mouse.

In addition, there are discrepancies of phenotypes between Cthrc1 transgenic mice which we generated in this study and the transgenic mice overexpressing Cthrc1 previously reported [14].

To examine the potential functions of Rbpj in mouse uteri, we generated a mouse model harboring a uterine-specific deletion of Rbpj (Rbpj d/d) by crossing Rbpj-loxp mice (Rbpj f/f) with PR-Cre mice (PR-Cre +/−).

To reveal the importance of SNAP-23 function in mouse development, we generated Snap23-null mice by homologous recombination.