Sentence examples for mice we created from inspiring English sources

To gain more insights in the mechanisms of synaptic and neurogenesis disturbances in STOP null mice, we created a complete degeneration of the OE of the right nasal cavity in 3- and 10-month-old animals and analysed two months later epithelial regeneration and glomerular structure.

Using RNA interference (RNAi) to knock down dystrophin in myotubes from C57BL10 mice, we created a homogenous model to study the transcriptome of dystrophin-deficient myotubes.

When we conducted pathway analysis on the list of 93 probesets that showed highly significant differences between the two strains of mice, we created a network in which IFN-γ and TNF-α were the most central (i.e., had the most connections to other genes in the network).

For each mouse, we created a positive cell density map (PCDM) at each of the five levels from the bregma (+2, +1, 0, −1, and −2±0.2 mm).

For the purpose of comparing a subset of human bimodal genes with those identified in mouse, we created a microarray dataset with comparable tissue samples to those used in the mouse study (Table 1) [ 1].

These mice were bred to TRETight-H2B/GFP transgenic mice that we created in the NCI-Frederick animal facility.

To generate the tetracycline (tet -regulatable Cdc42 tet -regulatable model we Cdc42ed transgenicing construct.

In order to test the effects of CaM-peptide in an HD transgenic mouse model, we created an AAV which mediates the expression of CaM-peptide.

While generating the R49C knock-in mice, in which the floxed neo cassette was deleted by mating with Cre deletor mice, we serendipitously created WT/R49Cneo and R49Cneo/R49Cneo mouse cataract models which show milder lens effects in vivo, thus allowing examination of the effects of the mutant protein at potentially changed levels of expression.

Heteroplasmic mice were obtained from a heteroplasmic mouse line (HB) we created previously by ooplasmic transfer (Burgstaller et al., 2014).

The effect of human IL6 on growth and diet-induced obesity in mice To investigate the effect of hIL6 upon nutrient homeostasis, we created mice with sustained circulating hIL6 secreted predominantly from brain and lung (h IL6tg mice) by backcrossing wild-type C57BL/6J mice 12 times with MUP/h IL6 mice expressing human IL6 cDNA under the control of a mouse urinary protein gene promoter.