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Thus, to determine if more plaques are present in the CNS of CD4-knockout mice as compared with their CD8-knockout counterparts or wt C57BL/6 mice, we counted the number of observed plaques in the ON, SC and brain of CD4−/−, CD8−/−, and wt control mice.
To quantify the numbers of Pax6+ and CB+ interneurons in these mice, we counted them in standardized counting boxes.
In Imp1-mutant mice we counted 633 Pax6+ cells as compared to 121 Tbr2+ cells and 117 Tuj1+ cells in the same sections.
In wild-type mice we counted 617 Pax6+ cells as compared to only 55 Tbr2+ cells and 74 Tuj1+ cells in the same sections.
To quantify oocyte numbers in Amhr2-Cre/+ Notch2 flox/- and control littermate mice, we counted serial sections of ovaries isolated at PND18.
To confirm that systemic injection of AAV9-hADAR2 prevented the degeneration of AHCs in the AR2 mice, we counted the axons in the ventral root of the fifth lumbar spinal segment (L5) and the number of AHCs in the L5.
Similar(52)
For all pairs of markers that are adjacent in human and mouse, we count the number of combinations in which the two markers are not adjacent in both, chimpanzee and rat.
To examine the fertility of the female Neat1 KO mice in detail, KO (n=10), wild-type (WT; n=9) or heterozygous (n=10) littermates were mated with C57BL/6 male mice, and we counted the number of parturition events and the number of offspring born over 26 weeks.
To demonstrate the effectiveness of our single best-section quantification method, we also quantified the total number of NPCs in the RMS of 20 randomly selected RI mice where we counted the number of BrdU + cells in every 10th section throughout the entire medial to lateral extent of the RMS.
We previously demonstrated that CD4+ T lymphocytes are present at end stage disease in mSOD1 mice; we rigorously counted lymphocytes in lumbar spinal cord sections and provided evidence that not only are CD4+ T lymphocytes increasing but also are CD8+ lymphocytes (Beers et al., 2008).
To evaluate the differences in zygotic activation between mice and pigs, we counted the number of up- and down-regulated genes at different stages of early cleavage development.
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