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Their research, based on tests in mice, was reported by a team led by Hualan Chen of the Animal Influenza Laboratory of the Chinese Ministry of Agriculture in yesterday's issue of the Proceedings of the National Academy of Sciences.
The anti - nociceptive effect of 7, 2′, 3′ – trimethoxy flavone, 7, 2′, 4′ – trimethoxy flavone, 7, 3′, 4′ – trimethoxy flavone and 7, 5, 4′ – trimethoxy flavone against inflammatory, neurogenic and thermal pain in mice was reported earlier.
Calbindin D9k (CB9k) and D28k (CB28k) are intracellular soluble calcium-binding proteins, whose expressions are considered to be regulated by vitamin D. However, the amount of CB28k expression in the kidneys of vitamin D receptor-null mice was reported to be similar to that in wild type mice, suggesting no dependence on vitamin D for its expression in kidneys.
The median lifespan of Nrf2 knockout mice was reported to be 106 weeks [43].
No special phenotype of adult mice was reported in that study.
The creation of the Ngn2 transgenic mice was reported elsewhere (ref guillemot).
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The Irf3−/− mice were reported previously63.
Plxnd1+/o and Sema3E+/o mice were reported in ref. 29.
In previous studies, GlastCreER T2 mice were reported to selectively modify α-tanycytes without obvious recombination in β-tanycytes40.
Extensive fibrosis observed in the Lepob/ob/Sesn2−/− mouse liver was particularly striking because Lepob/ob mutant mice were reported to be very resistant to liver fibrosis3.
Geraldol, the O-methyl metabolite of fisetin in mice, is reported to suppress endothelial cell migration and proliferation.
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