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Indeed, a deaf child who has many of the abnormalities identified in the COUP-TFI−/− mice was recently discovered to have a chromosomal microdeletion of the entire COUP-TFI locus [12].
The contribution of B cells and autoantibodies for inflammation pathogenesis in scurfy mice was recently highlighted.
Most notably, a strong association of epigenetic marks with long intergenic non-coding RNAs (lincRNAs >200 nucleotides) in humans and mice was recently described [ 9- 11].
An extensive project, sponsored by the National Toxicology Program, of the photocarcinogenic potential of HAs in SKH-1 mice was recently completed.
The ahl4 locus, which could explain about 40% of the ABR threshold variation in these mice, was recently identified as a mutation in the gene of Cs (Noben-Trauth & Johnson, 2009; Johnson et al., 2012).
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3MST-knockout mice were recently reported as a model for human mercaptolactate-cysteine disulfiduria45 and these mice should be a useful tool for investigating the physiological roles of 3MST.
Moreover, p21 null mice were recently shown to have a highly regenerative phenotype similar to that of MRL mice.
Diurnal activity patterns in house mice were recently observed to persist for months under semi-natural conditions with competition for food access [35].
Likewise, single and combined IR family knockout models in mice were recently established [20], suggesting that the IRR could function as an auxiliary member of the IR family, a role that may extend to other co-expressed recognition molecules, such as the TrkA receptor [21], [22].
Ephrin-A1 knockout mice were recently generated.
Oshima established the present mouse model, and cancers in these Gan mice were recently shown to belong to the intestinal type according to Laurén's classification [ 31].
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