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The generation of C57BL/129SvJ DAT knockout mice was previously described5, and these animals were intercrossed for >10 generations.
The generation of the Mmp13-, Plg- and Plau-deficient mice was previously described [18], [21], [39].
Generation of AMPKα1−/− [36] and AMPKα2−/− [37] mice was previously described.
The construction of the plasmid containing the Dbl oncogene cDNA under the control of the MT promoter and the generation of the transgenic mice was previously described [11].
A strong associaton of Mest with adiposity in adult mice was previously found by our laboratory and others [21], [22], [31].
Implantation of human multipotent stromal cells from bone marrow (hMSCs) into the dentate gyrus of the hippocampus of mice was previously shown to stimulate proliferation, migration and neural differentiation of endogenous neural stem cells.
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Sgca null, Nfix null, mdx, and Tg Mlc1f-Nfix2 mice were previously described17, 26, 35, 42.
Gal3−/− mice were previously generated as described and bred on the C57BL/6 mouse background for nine generations48.
CCSP-rtTA mice were previously described [23].
NOD-gld/gld mice are previously described [49].
Cln3Δex7/8 mutant mice were previously described [32].
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